Palo Alto Networks announces that Unit 42® Continuous Frontier AI Defense and Prisma AIRS™ are now on the newly launched OpenAI Marketplace, making them directly available to OpenAI’s enterprise customers. Threat actors are deploying artificial intelligence to find and exploit vulnerabilities at unprecedented speed, compressing breach cycles by almost 97%—from weeks down to mere hours. Human-speed defense can no longer keep pace with adversaries executing automated, continuous attacks.
AI Investments: The OpenAI Marketplace Advantage
For enterprise organizations holding OpenAI spend commitments, this milestone offers a compelling 2-for-1 financial and strategic advantage. Security teams can now deploy machine-speed, proactive defense while retiring their pre-committed OpenAI spend.
Palo Alto Networks offers two flagship solutions available for procurement through the OpenAI Marketplace.
- Unit 42® Continuous Frontier AI Defense: An always-on, expert-led agentic offensive security service that uses defender-grade models to discover, validate, and accelerate the remediation of exposures across applications and network assets before weaponization.
- Prisma® AIRS™: A comprehensive AI security platform designed to provide complete discovery, risk assessment, runtime protection, identity and data governance, and observability for AI applications, agents, models, and artifacts across enterprise cloud platforms, SaaS environments, and endpoints.
Machine-Speed Defense with Unit 42 Continuous Frontier AI Defense
Unit 42 Continuous Frontier AI Defense is an expert-led, agentic offensive security service engineered to identify, validate, and remediate enterprise exposures as an organization’s environment changes.
This always-on, agentic service combines our offensive security experts with our proprietary multi-model harness, which uses defender-grade frontier models to discover vulnerabilities, validate real-world exploitability, and accelerate remediation across applications, identities, cloud infrastructure, and network assets as an organization’s environment changes. At the core of this capability is our proprietary multi-model software harness that dynamically routes security tasks to the optimal AI model, maximizing efficacy and coverage while managing the cost of frontier AI at scale.
The harness integrates defender-grade models, including OpenAI’s GPT-5.6-Cyber, and other commercial models alongside open-weight models and Unit 42 threat intelligence. By executing non-destructive adversary simulations across first- and third-party environments, the system proves actual exploitability and delivers prioritized remediation guidance including actionable fixes, code-level changes, and virtual patches. Organizations can pair this with Frontier Virtual Patching to block exploits long before official patches exist or CVEs are publicly disclosed.
The real-world impact of this proactive methodology was validated over six months of in-house testing and across more than 75 customer engagements backed by a $17 million R&D investment. During internal deployment within Palo Alto Networks, the service uncovered over two years’ worth of exposures in just three weeks. In customer assessments, the underlying analysis identified exposures in 100% of assessed organizations, with 37% rated high or critical severity. Crucially, over two-thirds of exposures found in third-party applications had no known CVE, proving the urgent necessity of continuous, AI-driven discovery.
Unit 42 Continuous Frontier AI Defense is available worldwide today on an annual subscription basis. Register for our upcoming Virtual Threat Briefing to see how we apply Frontier AI, our proprietary multi-model harness, and offensive security expertise to protect Palo Alto Networks and our customers.
To learn more about Unit 42 Continuous Frontier AI Defense, register for the upcoming Virtual Threat Briefing here.
Scale Enterprise AI Adoption Safely with Prisma AIRS
As OpenAI customers rapidly scale their use of powerful AI models, AI coding assistants, and autonomous agents, the enterprise attack surface is expanding faster than traditional security teams can manage. The transition to autonomous AI breaks traditional security boundaries, creating shadow AI blind spots, supply chain risks in open-source base models, unsafe actions from malicious inputs, and uncontrolled AI agents executing tasks with excessive permissions.
Prisma AIRS: Secure Every AI Ambition
Prisma AIRS is the Palo Alto Networks unified AI security platform, enabling enterprises to accelerate AI adoption while maintaining control over sensitive data, agent identities, autonomous actions and AI costs. Recognized by Gartner as a Market Shaper in the September 2026 Emerging Market Quadrant for AI Application Security – Established Vendors, Palo Alto Networks brings together discovery, continuous risk assessment, real-time protection and centralized governance to secure AI applications and agents across enterprise environments.
- Gain Visibility Across Enterprise AI: Discover and inventory AI applications, coding assistants, autonomous agents and associated assets across endpoints, cloud and enterprise environments. Identify shadow AI and gain visibility into the AI systems operating across the organization.
- Identify Risks Before They Become Threats: Continuously assess AI security posture, scan models and agent artifacts—including skills and MCP servers—for vulnerabilities and supply chain risks, and proactively red team AI applications and agents to uncover exploitable weaknesses before deployment.
- Secure AI Interactions, Data and Agent Identities: Enforce real-time protection against prompt injection, malicious interactions and sensitive data exposure. Verify agent identities, enforce least-privilege access and prevent unauthorized actions as agents interact with enterprise systems and data.
- Centralize AI Policy, Access and Spend: Use AI Gateway to govern connections to LLMs, MCP servers, APIs and enterprise services. Centralize policy enforcement, control model and provider access, monitor consumption and manage AI usage and costs across teams and applications.
Together, these capabilities help OpenAI enterprise customers secure AI-powered workflows, maintain accountability for autonomous actions and scale AI adoption with consistent security and governance.
Book a demo to see our AI Security solution in action.